The impact of antimicrobial resistance in Clinical Research and the Pharmaceutical Industry
Introduction Antimicrobial resistance is a global public health issue of unprecedented severity. It is defined as the phenomenon where a microbe evolves to become more or fully resistant to antimicrobials that previously could treat it. Antimicrobials include antibiotics, which kill or inhibit the growth of bacteria. As a result, infections that were once easily treatable […]
The Essential Collaboration: The Role of Principal and sub-Investigator(s) in Clinical Trials
Introduction Clinical trials are a fundamental part of the process for developing new medications and medical devices, ensuring their efficacy and safety before they reach the market. The Principal Investigator (PI) is at the heart of these trials and is responsible for overseeing the study at the investigative site. However, the PI does not work […]
Psychiatric clinical trials: addressing methodological challenges
Introduction Psychiatric clinical trials are vital to advancing the treatment and understanding of mental health disorders. This emphasizes the need for biomarkers to enhance psychiatric treatments, particularly for disorders like schizophrenia and depression, where identifying specific subtypes could lead to more targeted and effective therapies [1], but they often face serious methodological challenges that can […]
The future of cancer treatment: Insights from immunotherapy trials
INTRODUCTION Cancer remains one of the most significant challenges in modern medicine, affecting millions of lives globally each year. , with an estimated 1.9 million new cases and 609,360 deaths in the United States in 2022 alone, according to the American Cancer Society’s Cancer Facts & Figures 2022 report [1]. his complex disease encompasses a […]